|Aug 29||Eduardo||Genome-wide scan of 29,141 African Americans finds no evidence of selection since admixture. Bhatia et al. arXiv|
|Aug 22||Priya||Recombination in the Human Pseudoautosomal Region PAR1. Hinch et al. PLoS Genetics 2014.|
|Aug 15||Sonal||Genetics of ecological divergence during speciation. Arnegard et al. Nature 2014.|
|Aug 8||Daniel Hooper||The genomic landscape underlying phenotypic integrity in the face of gene flow in crows. Poelstra et al. Science 2014. (Supplemental Material)|
|Aug 1||None||Statistical Genetics seminar given by Iain Mathieson (Reich lab)|
|July 25||Shai||Altitude adaptation in Tibetans caused by introgression of Denisovan-like DNA Huerta-Sanchez et al., Nature 2014. SOM.|
|June 27||Eyal||Poxviruses deploy genomic accordions to adapt rapidly against host antiviral defenses Elde et al., Cell 2012.Rules of engagement: molecular insights from host-virus arms races Daugherty and Malik, Annual Reviews 2012.|
|June 20||none||Statistical Genetics seminar given by Ilan Gronau (Siepel lab, Cornell)|
Precise estimates of mutation rate and spectrum in yeast. Zhu et al. PNAS 2014
|LAB MEETINGS||GIVEN BY:|
|Sept 12||Hila Sheftel, Weizmann Institute — beginning promptly at 9a
Statistical Genetics Seminar to follow
|Aug 15||Daniel Hooper (Price lab, U. Chicago)|
|Aug 1||PJ Perry (Penn State)|
|July 25||Adam Auton (Einstein)|
|June 13||Christina Bergey (Disotell lab, NYU)|
|June 6||none – NYU Annual Symposium in Genomics –|
|May 30||Yuri Pritykin (Singh lab, Princeton)|
|May 9||none – Biology of Genomes –|
|May 2||Eli Stahl (Mount Sinai)|
|April 4||Guy A. *from 10:30-12 in Fairchild 800*|
|Mar 28||Molly Schumer (Andolfatto lab, Princeton)|
|June 6||none||– NYU Annual Symposium in Genomics –|
|May 30||Amy||Transmission Distortion Affecting Human Noncrossover but Not Crossover Recombination: A Hidden Source of Meiotic Drive Odenthal-Hesse et al. PLoS Genet 2014.|
|May 9||none||– Biology of Genomes –|
|May 2||Molly S.||doublesex is a mimicry supergene Kunte et al. Nature 2014.|
|April 25||none||Eimear Kenny (Mount Sinai) @ Statistical Genetics|
|April 18||Joe||LD Score Regression Distinguishes Confounding from Polygenicity in Genome-Wide Association Studies Bulik-Sullivan et al. bioRxiv 2014.|
|April 11||Guy S.||Searching for missing heritability: designing rare variant association studies. Zuk et al. PNAS 2013.|
|Mar 28||Amir||Strong selective sweeps associated with ampliconic regions in great ape X chromosomes Nam et al. arXiv 2014.|
A Genetic Atlas of Human Admixture History. Hellenthal et al. 2014.
Mendelian randomization: prospects, potentials, and limitations. Smith and Ebrahin, 2004.
Causal Effects of Body Mass Index on Cardiometabolic Traits and Events: A Mendelian Randomization Analysis. Holmes et al., 2014.
|Feb 7||Yuval||Evaluating empirical bounds on complex disease genetic architecture. Agarwala et al. Nature Genetics 45: 1418-27.|
|Jan 31||Joe||Joint analysis of functional genomic data and genome-wide association studies of 18 human traits. Joseph Pickrell 2013. bioRxiv. dio: 10.1101/000752.|
|Jan 23||Min||Error-prone polymerase activity causes multinucleotide mutations in humans. Harris and Nielsen 2013.|
|Jan 22||Amy||Practice talk|
Great ape genetic diversity and population history. Prado-Martinez et al. 2013. Nature. 499(7459):471-5.
|Dec 9||Speaker: Pleuni Pennings, Postdoc with Dmitri Petrov|
|Dec 5||Speaker: Anand Bhaskar, Ph.D. student with Yun Song|
|Nov 21||Guy S.||
Why we are not dead one hundred times over. Charlesworth 2013. Evolution. 67(11):3354-61.
|Nov 14||Guy A.||
Contamination of the genome by very slightly deleterious mutations: why have we not died 100 times over? Kondrashov 1995. J Theor Biol. 175(4):583-94.
A Model-Based Analysis of GC-biased Gene Conversion in the Human and Chimpanzee Genomes. Capra et al. 2013. PLoS Genet. 9(8):e1003684.
Evidence of Abundant Purifying Selection in Humans for Recently Acquired Regulatory Functions. Ward and Kellis 2012. Science 337 (6102): 1675-1678.
Comment. Green and Ewing 2013. Science 340 (6133): 682.
Response to comment. Ward and Kellis 2013. Science 340 (6133): 682.
|Oct 15||Amy||Using extended genealogy to estimate components of heritability for 23 quantitative and dichotomous traits. Zaitlen et al. 2013. PLoS Genet. 9(5):e1003520.
|Oct 8||Min||Estimating human mutation rate using autozygosity in a founder population. Campbell et al. 2012. Nat Genet. 44(11): 1277–1281.
Whole-genome sequencing in autism identifies hot spots for de novo germline mutation. Michaelson et al. 2012. Cell 151(7):1431-42. http://www.ncbi.nlm.nih.gov/pubmed/23260136
Revising the human mutation rate: implications for understanding human evolution. Scally and Durbin 2012. Nat Rev Gen 13(10):745-753. http://www.ncbi.nlm.nih.gov/pubmed/22965354
|June 10||Ellen||Genetic recombination is targeted towards gene promoter regions in dogs. Auton et al. 2013. arXiv. http://arxiv.org/abs/1305.6485|
|June 3||Ziyue||Length distributions of identity by descent reveal fine-scale demographic history. Palamara et al. 2012. Am J Hum Genet. 7;91(6):1150.
|May 28||Marie||Recurrent rearrangement during adaptive evolution in an interspecific yeast hybrid suggests a model for rapid introgression. Dunn et al. 2013. PLoS Genet, 9(3):e1003366.
|May 20||Daniel||Hybrid speciation and independent evolution in lineages of alpine butterflies. Nice et al. 2013. Evolution, 67: 1055–1068.
|May 13||Amir||Genomic Tests of Variation in Inbreeding Among Individuals and Among Chromosomes. Schraiber et al. 2012. Genetics. (192): 1477–1482.
|May 6||Wynn||Genetic Architecture of Skin and Eye Color in an African- European Admixed Population. Beleza et al. 2013. PLOS Genet. 9(3): e1003372.
|May 2||Laure||Genomic evidence of rapid and stable adaptive oscillations over seasonal time scales in Drosophila. Bergland et al. 2013. arXiv.
|Apr 24||Daniel||A Y-like social chromosome causes alternative colony organization in fire ants. Wang et al. 2013. Nature 493, 664-668.
|Apr 8||Ziyue||Estimating selection coefficients in spatially structured populations from time series data of allele frequencies. Mathieson et al. 2013. Genetics 193(3), 973-984.
|Apr 2||Keerthi||A framework for variation discovery and genotyping using next-generation DNA sequencing data. DePristo et al. 2011. Nature Genetics 43, 491–498.
|Mar 20||Amir||Human aneuploidy: mechanisms and new insights into an age-old problem. Nagaoka et al. 2012. Nat Rev Genet 13(7):493-504. http://www.ncbi.nlm.nih.gov/pubmed/22705668|
|Mar 4||Wynn||Long-term exposure to antibiotics has caused accumulation of resistance determinants in the gut microbiota of honeybees. Tian et al. 2012. MBio. Oct 30;3(6). http://www.ncbi.nlm.nih.gov/pubmed/23111871|
|Feb 20||Ellen / Laure||A sequence-based approach demonstrates that balancing selection in classical human leukocyte antigen (HLA) loci is asymmetric. Bronson et al. 2013. HumMolGenet 22(2):252-61. http://www.ncbi.nlm.nih.gov/pubmed/23065702|
|Feb 4||Ellen||Discrete genetic modules are responsible for complex burrow evolution in Peromyscus mice. Weber et al. 2013. Nature 493(7432):402-405. http://www.ncbi.nlm.nih.gov/pubmed/23325221|
|Jan 30||Amir||Ancient admixture in human history. Patterson et al. 2012. Genetics 192:1065–1093 http://www.ncbi.nlm.nih.gov/pubmed/22960212|
|Jan 21||Daniel||Practice talk.|
|Jan 14||Laure||Genetic history of an archaic hominin group from Denisova Cave in Siberia. Reich et al. 2010. Nature 468(7327)
|Jan 7||Daniel||Mutations in the neverland Gene Turned Drosophila pachea into an Obligate Specialist Species. Lang et al. 2012. Science 337:1658-1661
The genomic landscape of species divergence in Ficedula flycatchers
Using environmental correlations to identify loci underlying local adaptation
Distinguishing between Selective Sweeps from Standing Variation and from a De Novo Mutation
Genetic recombination is directed away from functional genomic elements in mice
A direct characterization of human mutation based on microsatellites
Genome Patterns of Selection and Introgression of Haplotypes in Natural Populations of the House Mouse (Mus musculus)
The many landscapes of recombination in Drosophila melanogaster
+Classical genetics meets next generation sequencing: uncovering a genome-wide recombination map in Drosophila
Insect herbivores drive real time ecological and evolutionary change in plant populations
+ Natural enemies drive geographic variation in plant defenses
+ How insect herbivores drive the evolution of plants
Distortions in Genealogies Due to Purifying Selection
Dynamics of disease resistance polymorphism at the Rpm1 locus of Arabidopsis
Evidence of widespread selection on standing variation in Europe on height-associated SNPs